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- . , . , , , .

() ; . , . . : , .

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, , 2025 . . . - , .

, , (. 55.1). - . , 610 . - -. , , , . - , . ( ), , .

. 55.1. (Oncley).

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. 5, , , . , - - ( ); (. 55.2). .

(. . 54). -. , .

, (. . 26). - -. , . , , .

, (- ), , , .

, , , , (). . . , .

. 1,25- D3, (. . ).

, , , . .

. 26.

. 55.2. . . . . . . . . , -, -, - -. (Reproduced, with permission, from Stites D.P., Stobo J. D., Wells J. V. (eds). Basic and Clinical Immunology, 6th ed. Appleton and Lange, 1987.)

, , - . .

(L) (. 23 000) () (. 5300075000), (. 55.3). , . , , (CL), - (V,). , -, - (VH), 3/4 , , - , .. V,, -. , , . . 55.3, - , -, .

CL (. 55.1). -, -. -.

() (. 55.1), -. , , ; . 50000 75000 (. 55.1). (I- - , . , , . : IgG, IgA, IgM, IgD IgE. . 55.1, - -.

, VL- -, . , ( ), . , , .

. 55.3. : . V ; ї ; . - L-; . (Modified and reproduced, with permission, from Stites D. P., Stobo J. D., Wells J. V. (eds.). Basic and Clinical Immunology, 6th ed. Appleton and Lange, 1987.)

55.1. . (Reproduced, with permission, from Stites D. P., Stobo J. D., Wells J.V. (editors). Basic and Clinical Immunology, 6th ed., Appleton and Lange, 1987.)

: - -, - - -. . , . , ( ) (. 55.4). , .

, ( ), -, , (. 55.2). , IgG, . (IgA IgM) , (IgA) (IgM) (. 55.5).

. 55.4. IgG, . (Modified and reproduced, with permission, from Stites D. P., Stobo J. D. Wells J. V. (eds.). Basic and Clinical Immunology. 6th ed. Appleton and Lange. 1987.)

55.2. . (Reproduced, with permission, from Stites D. P., Stobo J. D., Wells J. V. (editors): Basic and Clinical Immunology, 6th, ed. Appleton and Lange, 1987.)

(. )

. 55.5. . ; . (Reproduced, with permission, from Stites D. P., Stobo J.D., Wells J. V. (eds.). Basic and Clinical Immunology, 6th ed. Appleton and Lange, 1987.)

, - , ( ) (. 55.1).

: (V,), (J) ( J- IgA IgM) (CL). : (VH), (D), (J) , . , , . 38 41.

. , , VH -.

, ( ) . - - (- - - , -, , -, VH. , . (IgM, IgG IgA), , () ()

; (). , - - -. . 41 , -.

, . , ( ). , - (, IgA IgG), (IgA, IgD, IgE, IgG, IgM). , . .

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