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, , , - (. 37.6). , .

1. , , , 2- ( ).

2. . , , , . ( , ) , .

3. ( , ), ( ) , , (. 37.7).

. 37.6. (), (), (U), () (- , , N- . : , 5- - .

4. , , , .

5. 2, - ; 2, , 5-, - 2- ; ( ) , .

, , (. . ) . , . () , . ( U) (. 37.8).

. . , , (). ʗ () - (, ). () () .

ʗ , , , - .

. 37.7. (), .

, . , 90 300 (. 37.3).

. - . , , , -, - - ( ) -. - , -.

: ( ) (), () (). , .

() - . - . , . . (. 37.9).

, , . 5- 7-, 5- 2-0- (. 37.10). 6- 2-0- . , , 5- . 5'-() . (-) 20250 . . , . , poly (). poly () oligo (), . poly ()- oligo ().

. 37.8. -. , . -, ( 3 - 5) ( U) .

. 37.9. - .

(. )

. 37.10. , 5- 7- 5- . 2-- .

, , , , . , . , , . . , 2106. , , .

() 75 . . - (. . 39). . 20 . ( ) 20 , . , . , , (. 37.11).

. - . , , (. 37.7). (. . 40) . D- - , - --. . 1 (75% ) 35 . - 2 1321 .

. 37.11. -, 3-- . , - . (From J. D. Watson. Molecular biology of the Gene 3rd, ed.. Copyright 1976, 1970, 1965 by W. A. Benjamin, Inc., Menlo Park Calif.)

, , , - , D ( ) .

. , , .

. , -. , , .

. 37.2 , 4,210 6 ( ).

37.2.

(60S), , (40S). 608- 58- (), 5,8S-pPHK 28S-pPHK, 50 . , 408- 18S-pPHK 30 . , 5S-PHK, 45S-PHK, (. . 40). 5S-PHK . . .

. , , . , . 90 300 , 1000001000000 .

( snurps . small nuclear ribonucleic particles), , . U7, -, - . , , , a (. . 39). . 37.3. .

37.3. ,

Darnell J. et al. Molecular Cell Biology, Scientific American Books, 1986.

Hunt T. DNA Makes RNA Makes Protein, Elsevier, 1983. Lewin B. Genes, 2nd ed., Wiley, 1985.

Rich A. et al. The chemistry and biology of left-handed Z-DNA, Annu. Rev. Biochem., 1984, 53, 847.

Turner P. Controlling roles for snurps, Nature, 1985, 316, 105. Watson J. D. The Double Helix, Atheneum, 1968.

Watson J. D., Crick F.H.C. Molecular structure of nucleic acids. Nature, 1953, 171, 737.

Zieve G. W. Two groups of small stable RNAs, Cell, 1981, 25, 296.

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